Socket Error 10060 thrown by Citrix XenApp when accessing Hyperion system with ZPA

Customers will soon have their VPN (netscaler) decommissioned and replaced by ZPA. Because of this, only ZPA or VPN will turned on at once. If customer encounters difficulty connecting to private application with ZPA, they will turn it off and use netscaler instead.

One of the End customer got this error when he is trying to these 3 applications with ZPA on but everything is working properly with VPN on , ZPA off.

Application :

Error message :

The IP/FQDN and port of these applications are unknown as the site itself is managed by customer’s partner. Any suggestion to move forward.